This study investigates the potential of microalloying to control the ion release of a palladium-based metallic glass (Pd-MG). Silver and gallium are used as microalloying elements known for their antibacterial properties. Studies of ion-release kinetics, thermal and mechanical properties, formability, and corrosion behavior show that microalloying is a viable strategy to control ion release from metallic glasses. There is potential to maintain the optimal physical properties of metallic glasses while enhancing their antibacterial functionalities and biocompatibility. The study opens avenues for the development of advanced implant materials with improved mechanical strength, durability, and increased antibacterial response.