In order to establish a strong cell-material interaction, the surface topography of the implant material plays an important role. This contribution aims to analyze the formation kinetics of nickel and beryllium-free Ti- and Zr-based Bulk Metallic Glasses (BMGs) with potential biomedical applications. The surface patterning of the BMGs is achieved by thermoplastic net-shaping (TPN) into anisotropically etched cavities of silicon chips. The forming kinetics of the BMG alloys is assessed by thermal and mechanical measurements to determine the most suitable processing temperature and time, and load applied. Array of pyramidal micropatterns with a tip resolution down to 50 nm is achievable for the Zr-BMG, where the generated hierarchical features are crucial for surface functionalization, acting as topographic cues for cell attachment. The unique processability and intrinsic properties of this new class of amorphous alloys make them competitive with the conventional biomaterials.