A detailed understanding of the drilling fluid rheology and filtration properties is essential to assuring reduced fluid loss during the transport process. As per literature review, silica nanoparticle is an exceptional additive to enhance drilling fluid rheology and filtration properties enhancement. However, a correlation based on nano-SiO2-water-based drilling fluid that can quantify the rheology and filtration properties of nanofluids is not available. Thus, two data-driven machine learning approaches are proposed for prediction, i.e. artificial-neural-network and least-square-support-vector-machine (LSSVM). Parameters involved for the prediction of shear stress are SiO2 concentration, temperature, and shear rate, whereas SiO2 nanoparticle concentration, temperature, and time are the inputs to simulate filtration volume. A feed-forward multilayer perceptron is constructed and optimised using the Levenberg–Marquardt learning algorithm. The parameters for the LSSVM are optimised using Couple Simulated Annealing. The performance of each model is evaluated based on several statistical parameters. The predicted results achieved R2 (coefficient of determination) value higher than 0.99 and MAE (mean absolute error) and MAPE (mean absolute percentage error) value below 7% for both the models. The developed models are further validated with experimental data that reveals an excellent agreement between predicted and experimental data.