Integrated approaches to research set a common goal, which, in the case of the EURECA-PRO programme, is to work towards realising Sustainable Development Goal (SDG) 12, Responsible Consumption and Production (RCP). However, the diversity of perspectives, expectations, and work methods within all types of cross-disciplinary work can be challenging. Based on the work of the RE-EURECA-PRO project, which develops the research and innovation agenda of EURECA-PRO, this contribution provides an insight into the complexity, challenges, and opportunities of interdisciplinary research collaboration and transdisciplinary actions.