The core competences of a trading company often involve the logistic processes of order processing, storage and delivery. Therefore, they should be designed as efficiently and effectively as possible. Nevertheless, there is often a great potential for optimization, which may – depending on the objectives – result in large cost savings and increased customer satisfaction. Based on the current situation of Odörfer, the aim of this thesis is to find optimization potentials in terms of locations and delivery routes with the help of a simulation. The theoretical background of the thesis is based on the basics of modeling and computer simulation, site selection as well as warehousing and order picking systems. First of all, cost estimation for various logistic scenarios with the help of a simulation model is performed. Thus, a decision regarding delivery or routing can be supported. The basis for this simulation model is the “traveling salesman problem”, in which the shortest possible round trip for a specified number of destinations must be found. Owing to the possibility that various parameters such as start and end times of the routes, volumes of cargo trucks, etc. can be changed easily, a direct comparison of different scenarios can be realized. Another element of this work is the identification of potential sites for which another calculation model was created. This model is based on the objective of minimizing the time required for the supply of all customers for the desired number of locations. Furthermore, the thesis deals with the comparison of various picking systems which should be applied in the future enlargement of the storage capacity.