Product Lifecycle Management (PLM) systems are a common component in the IT landscape of many companies. To manage products over the whole product lifecycle, a data exchange between PLM systems and other enterprise applications is essential. The objective of this thesis is to provide a flexible solution that integrates the PLM system of Siemens Product Lifecycle Management Software Inc, Teamcenter, with enterprise applications. The first part of this thesis discusses the challenges of enterprise application integration and gives an overview of the currently available integration solutions. In the second part, some basics of Teamcenter are summarized. The main part of the thesis demonstrates an integration solution for Teamcenter that is built with the Apache Camel framework. Additionally, use cases examples are discussed. For each use case, enterprise integration patterns are used to design a solution, which is then realized in the Apache Camel framework.