Enhanced structural stability of DNA origami nanostructures by graphene encapsulation

Research output: Contribution to journalArticleResearchpeer-review

Authors

  • Borislav Vasić
  • Jelena Pesic
  • Julia Prinz
  • Ilko Bald
  • Aleksandar R Milosavljevic
  • Radoš Gajić

Organisational units

External Organisational units

  • University of Belgrade
  • Synchrotron Soleil, l'Orme des Merisiers
  • Institute of Chemistry, Universty of Potsdam
  • Bundesanstalt für Materialforschung und –prüfung (BAM)

Abstract

We demonstrate that a single-layer graphene replicates the shape of DNA origami nano structures very well. It can be employed as a protective layer for the enhancement of structural stability of DNA origami nano structures. Using the AFM based manipulation, we show that the normal force required to damage graphene encapsulated DNA origami nano structures is over an order of magnitude greater than for the unprotected ones. In addition, we show that graphene encapsulation offers protection to the DNA origami nano structures against prolonged exposure to deionized water, and multiple immersions. Through these results we demonstrate that graphene encapsulated DNA origami nano structures are strong enough to sustain various solution phase processing, lithography and transfer steps, thus extending the limits of DNA-mediated bottom-up fabrication.

Details

Original languageEnglish
Article number025016
Number of pages9
JournalNew journal of physics
Volume18.2016
Issue number2
DOIs
Publication statusPublished - 15 Feb 2016